Welcome to my blog

I have been working for many years in the field of drug development and optimization. I am an NMR spectroscopist and in the last 15 years I was applying high field nuclear magnetic spectroscopy for determination of 3D molecular structures and interaction of small ligands with receptor of relevant biological interest. During the last years I was mainly dedicated to the application of NMR for mixture analysis, in particular for metabolomics studies. Since September 2015 I held the position of Metabolomics and Chemometrics Solutions Product Manager at Mestrelab Research.

During 2014 I joined “Giardino della Scienza” of Ascona, an organization directed by Giorgio Häusermann. The aim of this organization is to organize didactic labs for kids of 6/10years old and 11/14 years old. Moreover Giardino della Scienza is actively involved in the annual event Asconosc(i)enza http://www.asconoscienza.ch, that is held around February/March in Ascona, Switzerland.

About Silvia

Silvia Mari obtained her PhD in Chemistry in 2006 at the Universidad Autonoma of Madrid (Spain) under the direction of Prof. Jesus Jimenez-Barbero. She focused her research in small molecules conformational research and protein-ligand interaction studies by Nuclear Magnetic Resonance (NMR). Particularly, in collaboration with the organic synthesis and computational chemistry partners, she focused her investigation in NMR structure-based drug design of glycomimetics of biological interest.

After a first post-doc period at the University of Milan, she was appointed at Dulbecco Telethon Institute c/o S. Raffaele Scientific Institute in Milan (Italy). Her research focused on development of advanced methods for monitoring in-vivo ligand-target interaction and structure determination and validation by NMR and implementation and application of NMR metabolomic in collaboration with different researching groups. She was involved in developing new computational tools to assist spectroscopist in metabolite assignment and mixture analysis (in collaboration with CCPN -The Collaborative Computing Project for NMR)  and she has now ongoing a collaboration with Mestrelab Research Company. Since 2007, she was involved in several grant applications both at national and international levels. Since 2009 she is involved in paper review in the field of NMR and metabolomics and has joint the Editorial Board of two international journals. She has published about 20 scientific publications (see her profile on Google Scholar).

In 2007 she was granted for the attendance to the course “Management and Enhancement of Results in Academia and Industrial Research” hold by Politecnico University of Milan and which topics included general tools for management like business planning, budget management and patent issue. Moreover, in 2011 she founded her own company called R4R (www.research4rent.com) with the aim to help connections between Pharma and Biotech companies and scientific excellences of leading Research Centers around the world in order to build synergistic partnerships for R&D applications.

The origin and growth of R4R comes from a personal experience between a small biotech company of the Milan area and a research group within San Raffaele Scientific Institute were I was working. This collaboration has lasted 3 years and brought important achievements both from the company perspective – results presented over years at the Advisory Board and related investment’ successes- and from the public research group – 3 salaries paid, several scientific publications and a founded project by the Italian Association for Cancer Research.

This positive experience generated the thought that collaboration between industry and academic research could positively exist. Moreover, if this collaboration is successfully managed it could bring important and fruitful results for both sides. This thought has been consolidated during these last years, particularly in the case of Italian recession of Pharmaceutical sector. From one hand industries have shown to cut off more and more also in the R&D departments; on the other hand academic groups, which have been founded in the past to get the state of the art of equipments, now have to face how to maintain these expensive technologies. Hence the possibility to create, or facilitate, a bridge between companies and research centers allows industry to get access to the excellence of the research, and it give the opportunity to research centers to keep their personnel and instrumentations.

My consulting activities are primarly oriented in NMR applications for mixture analysis.
I support clinical trials willing to introduce metabolomics approaches; Clinical trials provide samples and R4R manages spectral acquisition and data interpretation. Since 2015 I hold the position of Metabolomics and Chemometrics Solutions Product Manager for Mestrelab Research. I am interested in Benchtop NMR system and their possible  new applications.
I collaborate with Giardino della Scienza group in organizing educational labs for kids of primary and secondary school degrees.

Twitter

News

  • GoEco!

    GoEco!

    Si parte! Da lunedì 7 marzo GoEco! entra nel vivo La fase di reclutamento dei partecipanti al progetto sta per terminare e tra poco GoEco! entrerà nel vivo! Le attività di GoEco! partiranno infatti lunedì 7 marzo 2016, con un primo periodo di monitoraggio degli spostamenti dei partecipanti. Stiamo preparando alcuni brevi video di presentazione del progetto GoEco!, delle attività che svolgeremo assieme e di quello che succederà nei prossimi mesi. Assieme ai video a breve si potrà scaricare dagli store Google Play (Android) e App store (iOS) l‘app GoEco! Tracker, che useremo nel primo periodo di monitoraggio. Vi segnaliamo infine che le iscrizioni a GoEco! sono ancora aperte e chiuderanno venerdì 4 marzo 2016: avete dunque ancora qualche giorno per iscrivervi e invitare amici e parenti a partecipare assieme a voi. Vivere assieme l’esperienza GoEco! è molto più efficace, oltre che più divertente! […]

  • “Asconosc(i)enza 2016 è pronta a decollare per portarci molto lontano sia nel tempo che nello spazio. Il fascino dello spazio stellare, l’universo con i suoi mille interrogativi, la voglia dell’uomo di conoscerlo, di conquistarlo e [...]

  • Cena di Natale 2015

    Cena di Natale 2015

    Cena di Natale 2015 15 dicembre 2015 Cena di Natale 2015 La consueta Cena di Natale dell’AFTI per il 2015 avrà luogo martedì 15 dicembre 2015 presso il Ristorante Seven del Casinò Municipale di [...]

  • 37th Danish NMR meeting “Dansk Forening for Molekylspektroskopi”

    37th Danish NMR meeting “Dansk Forening for Molekylspektroskopi”

    37th Danish NMR meeting “Dansk Forening for Molekylspektroskopi” It is a pleasure to announce that Mestrelab will sponsor and attend the 37th Danish NMR conference at hotel Fuglsøcentret in Mols national park, in January [...]

  • “Towards Automating Small Molecule Structure Verification”

    “Towards Automating Small Molecule Structure Verification”

    “Towards Automating Small Molecule Structure Verification” FREE webinar on Thursday the 10th of December at 15.00 hrs (CET) Mestrelab is pleased to announce one more webinar for this 2015. Dr. Markus Schade,  Scientific Manager [...]

Events

YCC on Energy

January 1 - December 31

Activity

NMR in Analytical Chemistry

Sample handling, Spectra acquisition, and data processing

Are you working with biomolecules, small compounds, polymers or nanoparticles? Do you need to acquire any NMR spectra? Are you dealing with mixtures? Do you need Metabolomic Profiling Services?

Contact with us info@research4rent.com

MINT Learning Mathematics

Informatics, Natural sciences, and Technics

Knowledge is not only a privilege but also a responsibility. Prof. Bernd Gärtner at Kinderlabor” (Laboratory for Children)

Sezione dedicata al Giardino della Scienza, Programmazione per i più piccoli, laboratori didattici e robotica.

NMR in Analytical Chemistry

MINT Learning Mathematics

Talent wins games, but teamwork and intelligence wins champions
Michael Jordan
Never lose a holy curiosity.
Albert Einstein

Blog – Latest releases

GoEco!

By | February 25th, 2016|Categories: News|Tags: , |

Si parte! Da lunedì 7 marzo GoEco! entra nel vivo La fase di reclutamento dei partecipanti al progetto sta per terminare e tra poco GoEco! entrerà nel vivo! Le attività di GoEco! partiranno infatti lunedì 7 marzo 2016, con un primo periodo di monitoraggio degli spostamenti dei partecipanti. Stiamo preparando alcuni brevi video di presentazione del progetto GoEco!, delle attività che svolgeremo assieme e di quello che succederà nei prossimi mesi. Assieme ai video a breve si potrà scaricare dagli store Google Play (Android) e App store (iOS) l‘app GoEco! Tracker, che useremo nel primo periodo di monitoraggio. Vi segnaliamo infine che le iscrizioni a GoEco! sono ancora aperte e chiuderanno venerdì 4 marzo 2016: avete dunque ancora qualche giorno per iscrivervi e invitare amici e parenti a partecipare assieme a voi. Vivere assieme l’esperienza GoEco! è molto più efficace, oltre che più divertente! […]

By | February 23rd, 2016|Categories: News|Tags: , |

“Asconosc(i)enza 2016 è pronta a decollare per portarci molto lontano sia nel tempo che nello spazio. Il fascino dello spazio stellare, l’universo con i suoi mille interrogativi, la voglia dell’uomo di conoscerlo, di conquistarlo e [...]

Cena di Natale 2015

By | December 10th, 2015|Categories: News|

Cena di Natale 2015 15 dicembre 2015 Cena di Natale 2015 La consueta Cena di Natale dell’AFTI per il 2015 avrà luogo martedì 15 dicembre 2015 presso il Ristorante Seven del Casinò Municipale di [...]

37th Danish NMR meeting “Dansk Forening for Molekylspektroskopi”

By | December 10th, 2015|Categories: News|

37th Danish NMR meeting “Dansk Forening for Molekylspektroskopi” It is a pleasure to announce that Mestrelab will sponsor and attend the 37th Danish NMR conference at hotel Fuglsøcentret in Mols national park, in January [...]

“Towards Automating Small Molecule Structure Verification”

By | December 10th, 2015|Categories: News|

“Towards Automating Small Molecule Structure Verification” FREE webinar on Thursday the 10th of December at 15.00 hrs (CET) Mestrelab is pleased to announce one more webinar for this 2015. Dr. Markus Schade,  Scientific Manager [...]

MetaboMeeting 2015

By | December 10th, 2015|Categories: News|Tags: |

MetaboMeeting 2015 MetaboMeeting 2015 Date: Monday, 7 December 2015 - Wednesday, 9 December 2015 Location: Cambridge, UK The Metabolic Profiling Forum (MPF) announce the Metabomeeting 2015. Agenda Topics Advancing Biological Knowledge from Single Cells [...]

Il Giardino della Scienza a Sportech2016

By | December 10th, 2015|Categories: News|Tags: , , |

Il Giardino della Scienza a Sportech2016 Il Giardino della Scienza sarà a Sportech2016 per tutta la durata della manifestazione, da martedì 12 a venerdì 15 gennaio 2016. All’interno dei laboratori didattici ci troverete con [...]

Large scale facilities

By | November 25th, 2015|Categories: News|

Large scale facilities Are you working in the field of structure determination of biomolecules or the elucidation of their macromolecular complexes? Probably you’d be interested in the Transnational Access (TA) activities of the [...]

The Lairds of Learning by George Monbiot

By | November 25th, 2015|Categories: News|

The Lairds of Learning by George Monbiot During the last months my collegues and I were overhelmed by request from different scientific editorials to produce reviews, chapters book or to join directly editorial boards [...]

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1112, 2015

ISEF Fiera internazionale della scienza e dell’ingegneria di Phoenix

December 11th, 2015|0 Comments

ISEF Fiera internazionale della scienza e dell’ingegneria di Phoenix - 9-13 maggio 2016 Con la partecipazione di studenti italiani selezionati da I giovani e le scienze 2015 Per saperne di più

1112, 2015

I-SWEEEP – Fera internazionale ambiente energia ingegneria di Houston

December 11th, 2015|0 Comments

I-SWEEEP - Fera internazionale ambiente energia ingegneria di Houston - 26 aprile-1° maggio 2016 Con la partecipazione di studenti italiani selezionati da I giovani e le scienze 2015 Per saperne di più

1112, 2015

TISF – Fiera scientifica internazionale di Taipei

December 11th, 2015|0 Comments

TISF – Fiera scientifica internazionale di Taipei - 24-30 gennaio 2016 Con la partecipazione di studenti italiani selezionati da I giovani e le scienze 2015 Per saperne di più

1112, 2015

Expo sciences del Messico, Tampico

December 11th, 2015|0 Comments

Expo sciences del Messico, Tampico - 6-9 dicembre 2015 Con la partecipazione di studenti italiani selezionati da I giovani e le scienze 2015 Per saperne di più

1112, 2015

Speciale Giovani Scienziati

December 11th, 2015|0 Comments

I giovani e le scienze 2016 - 24 febbraio Selezione nazionale per il 28° EUCYS – Concorso dell’Unione europea dei giovani scienziati e per i più prestigiosi eventi internazionali degli studenti eccellenti . termine [...]

1112, 2015

YCC on Energy

December 11th, 2015|0 Comments

YCC on Energy - 1 gennaio – 31 dicembre conferenze per i giovani cittadini sull’energia iniziativa di Milset Europe con la collaborazione della Fast Come promuovere e valorizzare eventi condividendo i risultati con ragazze [...]

1112, 2015

Rifiuti: le nuove norme, le classi di pericolo e gli scenari di responsabilità

December 11th, 2015|0 Comments

Rifiuti: le nuove norme, le classi di pericolo e gli scenari di responsabilità - 14-15 dicembre L’iniziativa propone un approfondimento pratico sulla gestione dei rifiuti alla luce della nuova classificazione, approfondendo la gestione degli [...]

2511, 2015

Metabomeeting next 25th-28th September

November 25th, 2015|0 Comments

Metabomeeting next 25th-28th September Silvia Mari will attend at Metabomeeting next 25th-28th September in Helsinki: meet our President Agenda will include one poster presented: Poster n° 130 “THE CCPN METABOLOMICS PROJECT: A FAST PROTOCOL [...]

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Contact

Via Borgo 55
6612 Ascona – Switzerland

e-mail info@research4rent.com
mobile +41 79 508 80 46
mobile +39 347 0022353
skype silvia.mari.sciortino

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